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Our results suggest that blood-plaque interactions are critical in the development of atherothrombosis in mice, substantiating the argument that changes in blood coagulation status may have a determinant role in the onset of acute coronary syndrome..Postmortem pathological studies suggested that plaques with a thin fibrous cap, a large necrotic core, sparse smooth muscle cells and collagen within the cap, and infiltration of macrophages and lymphocytes, are likely to be unstable.Military and police hospitals, if any, are non-functional country wide, forcing soldiers and officers to share the limited facilities with civilians.Juba Teaching Hospital is directly funded by the central government through the National Ministry of Health.In a mouse model of plaque destabilization established in our laboratory, we targeted blood thrombogenicity by systemically overexpressing murine prothrombin via adenovirus-mediated gene transfer.

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In any case, it is when the freak can be sensed as a figure for our essential displacement that he attains some depth in literature.” words rise from a lone voice, growing from the small country church congregation, lying deep in the heart of the American South.

“Whenever I'm asked why Southern writers particularly have a penchant for writing about freaks, I say it is because we are still able to recognize one.

To be able to recognize a freak, you have to have some conception of the whole man, and in the South the general conception of man is still, in the main, theological.

The affected plaques displayed features of culprit lesions as seen in human coronary arteries, including fibrous cap disruption, luminal thrombosis, and plaque hemorrhage.

Treatment with aspirin and clopidogrel substantially reduced the incidence of atherothrombosis in this model.




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